By Martinez J. Hewlett, David C. Bloom, David Camerini Edward K. Wagner
Excellent for the scholar looking a fantastic realizing of the fundamental rules during this quickly constructing box, this best-selling textual content deals a accomplished creation to the basics of virology. that includes an greater artwork application now in full-color, the recent variation has been up-to-date all through. new version contains extra interpreting feedback, improved evaluate questions, bankruptcy outlines and full-colour art includes new chapters facing viruses and melanoma, new release and use of recombinant viruses and virus-like debris, viral evolution, community biology and viruses, and animal versions and transgenics, in addition to a bankruptcy dedicated to HIV and AIDS Downloadable paintings, unique animations and on-line assets can be found at www.blackwellpublishing.com/wagner
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Additional resources for Basic Virology, 3rd Edition
In some cases, cells can mount a defense against virus infection. Most animal cells react to infection with many viruses by inducing a family of cellular proteins termed interferons that can interact with neighboring cells and induce those cells to become wholly or partially resistant to virus infection. Similarly, some viral infections of bacterial cells can result in a bacterial restriction response that limits viral replication. Of course, if the response is completely effective, the virus cannot replicate.
The sum total of the virus-encoded functions that contribute to virus propaga- CHAPTER 1 INTRODUCTION – THE IMPACT OF VIRUSES ON OUR VIEW OF LIFE tion in the infected cell, in the host organism, and in the population is defined as pathogenicity of that virus. This term essentially describes the genetic ability of members of a given specific virus population (which can be considered to be genetically more or less equivalent) to cause a disease and spread through (propagate in) a population. Thus, a major factor in the pathogenicity of a given virus is its genetic makeup or genotype.
Roner, University of Texas, Arlington; Lyndon Larcom, Clemson University; Michael Lockhart, Truman State University; Lloyd Turtinen, University of Wisconsin, Eau Claire; and Paul Wanda, Southern Illinois University. All of these colleagues and friends represent the background of assistance we have received, leading to the preparation of this third edition. We would especially like to acknowledge Dr. Luis Villareal and the Center for Virus Research at the University of California, Irvine, for supporting our efforts in bringing this book to a timely completion.