Achieving Sterility in Medical and Pharmaceutical Products by Nigel Halls PDF

Achieving Sterility in Medical and Pharmaceutical Products by Nigel Halls PDF

By Nigel Halls

Detailing the clinical ideas underlying the success of sterility, this precise reference examines either a wide spectrum of functional, well-known sterilization methods and the equipment on hand to substantiate sterility-assessing the strengths and obstacles of every expertise. Delineates present regulatory standards for sterility-emphasizing the significance of aseptic procedures within the scientific institution and the pharmaceutical undefined! reaching Sterility in scientific and Pharmaceutical items discusses sterilization methods that make the most of ·saturated steam ·dry warmth ·ethylene oxide ·gamma radiation ·sterile filtration ·and extra!

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Additional info for Achieving Sterility in Medical and Pharmaceutical Products (Drugs and the Pharmaceutical Sciences)

Sample text

Title.  Series. 4’8—dc20 DNLM/DLC for Library of Congress 94-6372 CIP The publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales/Professional Marketing at the address below. This book is printed on acid-free paper. Copyright © 1994 by MARCEL DEKKER, INC. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher.

Mainly we are thinking here of diagnostic devices, bearing in mind that contamination could affect the patient through adversely influencing the outcome of the diagnostic process. (b) Devices that contact intact external surfaces, such as sterile dressings, or heavily contaminated internal surfaces such as the gut, for instance examination gloves. Patients are not really likely to die as a result of non-sterility of these products unless a chance contaminant has unusually invasive properties competitive with the innate microflora.

But can we reasonably infer that Pasteur’s clear organic infusions were necessarily sterile? The answer to this question is not straightforward. The clear infusions were clearly not contaminated by any microorganisms that had the capability of reproducing in these media under the conditions within which they were incubated. The question remains whether there might have been microorganisms present that if transferred to another medium, or incubated under different conditions, would have multiplied to discernable levels.

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